![]() ![]() For both NV models 1 and 2, 100 unique simulated patient populations were created, and the average of the statistical power of each population was calculated using the Stat-Power models. 5 NV model 1 may be helpful to generate patient diaries similar to what might be encountered in clinic, and NV model 2 may be more helpful for simulating RCTs, which often enroll "sicker" patients (ie, with higher typical seizure rates). ![]() 23 NV model 2 was designed similarly, but optimized to produce populations with higher seizure frequencies to match typical epilepsy RCTs. 5 Specifically, NV model 1 produces patients with a heterogeneity of average monthly seizure frequencies designed to match a large cross section of >10 000 epilepsy patients, 22 as well as exhibiting the "L-relationship," a power-law correlation between mean and standard deviation of seizure counts seen across multiple datasets. 13 NV model 1 was designed to match the general population of patients found in clinic, 13 whereas NV model 2 was designed to match the population of patients typically eligible for RCTs. Efforts to protect PWE during major public health emergencies should take these findings into account. Those with lower COVID-19 risk may have been marginalized more than those with higher risk. The COVID-19 pandemic presents unique challenges to PWE, including increased seizure rates, problems with access and cost of life-saving medications. Ten percent without generalized convulsions and 8% with did not know anything about epilepsy devices (VNS, RNS, DBS). ![]() Increased anxiety was reported in 47%, and increased depression in 28%. Lower-risk COVID patients reported more fear of hospitalization (55% versus 38%, p<0.001) and anxiety about medication access (43% versus 28%, p=0.03) compared with higher-risk COVID patients. Of the respondents, 5% reported stopping or reducing anti-seizure medications due to problems communicating with doctors, access or cost. Fear about hospitalization (53%) and concern for loved ones (52%) were prominent concerns. ![]() Mortality risks from COVID-19 had median OR of 1.67, ranging 1.00-906.98. Of these, 71% reported no change in seizure rates and 25% reported an increase in seizures, which they attributed primarily to disrupted sleep (63%) and decreased exercise (42%). Questions about demographics and medical history were used to calculate COVID mortality risk odds ratios (OR) compared to a low baseline risk group. We conducted a cross-sectional study using a 20-question survey that used, sent to eligible PWE and their caregivers on May 6th, 2020. This study sought to understand issues facing people with epilepsy (PWE) during the lockdown period of the COVID-19 pandemic in the United States. The benefits of the different formats were emphasised. Despite its disadvantages, imperfections and inadequacies, the paper-based diary is still relevant for managing patients with epilepsy in resource-limited settings.Ĭontribution: This study reviewed the literature to find the current norms and practices in using seizure diaries. The high cost of data and the expensive devices required to access electronic diaries make it unsuitable in a resource-limited setting. The two forms of diaries in use are electronic and paper-based diaries. The themes identified were types of seizure diaries used in clinical practice, contents and structure of a standardised seizure diary, the use and efficacy of seizure diaries in medicine and challenges relating to using a seizure diary for patient management.Ĭonclusion: The study revealed that a seizure diary remains a relevant tool in managing epilepsy. The majority (65%) of the articles were studies conducted in the United States. The majority (48%) of the studies were prospective studies. Results: A total of 1125 articles were identified from the database 46 full-text articles were assessed for eligibility, of which 23 articles were selected. Method: A scoping review was performed by screening relevant studies and identifying themes, categories and subcategories. This scoping review sought to identify current norms and practices for using seizure diaries to manage epilepsy. Healthcare practitioners look for effective ways to track patients’ seizures, and a seizure diary is one of the methods used. Background: Epilepsy is a chronic and debilitating condition affecting people of all ages in many nations. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |